横浜薬科大学 薬学部

最終学歴

金沢大学大学院　薬学研究科　修士課程（製薬化学専攻）

取得学位

薬学博士（東京大学）

所属学会

日本薬学会，日本化学会，有機合成化学協会，米国化学会

現在の専門分野

有機合成化学

現在の研究課題

生理活性天然物の構造と合成に関する研究
新規複素環化合物の合成研究

主要研究業績

融合キノリジジン環系アルカロイドの構造と合成
海洋生物由来生理活性天然物の構造と合成
サイトカイニン類の合成と植物ホルモン作用

最近の研究業績

1. Microhydration of the Guanine–Guanine and Guanine–Cytosine Base Pairs
   S. Urashima, H. Asami, M. Ohba, and H. Saigusa
   J. Phys. Chem. A, 114, 11231–11237 (2010)
2. Total Synthesis of the Proposed Structure of Macrocaffrine
   M. Ohba and I. Natsutani
   Tetrahedron, 63, 12689–12694 (2007)
3. Intramolecular Diels–Alder Reactions of Oxazole–Olefins: Synthesis of the Rauwolfia Alkaloids Suaveoline and Norsuaveoline
   M. Ohba, I. Natsutani, and T. Sakuma
   Tetrahedron, 63, 10337–10344 (2007)
4. Use of the Oxazole–Olefin Diels–Alder Reaction in the Total Synthesis of the Monoterpene Alkaloids (–)-Plectrodorine and (+)-Oxerine
   M. Ohba, R. Izuta, and E. Shimizu
   Chem. Pharm. Bull., 54, 63–67 (2006)
5. Diterpene-Containing Adenine Alkaloids
   M. Ohba
   Recent Res. Devel. Organic Chem., 9, 71–92 (2005)
6. Synthesis of Na-Demethyl-20-deethylsuaveoline, the Structure Proposed for Sellowiine
   M. Ohba and I. Natsutani
   Heterocycles, 63, 2845–2850 (2004)
7. Total Synthesis of Suaveoline and Norsuaveoline via Intramolecular Oxazole–Olefin Diels–Alder Reaction
   M. Ohba, I. Natsutani, and T. Sakuma
   Tetrahedron Lett., 45, 6471–6474 (2004)
8. Preparatory Study for the Synthesis of the Marine Sponge Alkaloids Asmarines A–F: Synthesis of Their Heterocyclic Portions
   M. Ohba and T. Tashiro
   Heterocycles, 57, 1235–1238 (2002)
9. Efficient Synthesis and Hydrolysis of Cyclic Oxalate Esters of Glycols
   T. Itaya, T. Iida, Y. Gomyo, I. Natsutani, and M. Ohba
   Chem. Pharm. Bull., 50, 346–353 (2002)
10. Reactions of Oxalyl Chloride with 1,2-Cycloalkanediols in the Presence of Triethylamine
    T. Itaya, T. Iida, I. Natsutani, and M. Ohba
    Chem. Pharm. Bull., 50, 83–86 (2002)
11. Effect of Copper(II) Triflate on Intramolecular Diels–Alder Reaction of Oxazole–Olefins
    M. Ohba and R. Izuta
    Heterocycles, 55, 823–826 (2001)
12. A New Access to Cyclopenta[c]pyridine Ring System: Syntheses of (–)-Plectrodorine and (+)-Oxerine
    M. Ohba, R. Izuta, and E. Shimizu
    Tetrahedron Lett., 41, 10251–10255 (2000)
13. A Chiral Synthesis of the Strychnos and Ophiorrhiza Alkaloid Normalindine
    M. Ohba, H. Kubo, and H. Ishibashi
    Tetrahedron, 56, 7751–7761 (2000)
14. A Modification of the Asymmetric Dihyroxylation Approach to the Synthesis of (S)-2-Arylpropanoic Acids
    H. Ishibashi, M. Maeki, J. Yagi, M. Ohba, and T. Kanai
    Tetrahedron, 55, 6075–6080 (1999)
15. Stereoselective Radical Cascade Approach to Benzo[a]quinolizidines
    H. Ishibashi, M. Inomata, M. Ohba, and M. Ikeda
    Terahedron Lett., 40, 1149–1152 (1999)
16. Synthetic Studies on the Starfish Alkaloid Imbricatine. A Chiral Synthesis of Tri-O-methylimbricatine
    M. Ohba, Y. Nishimura, M. Kato, and T. Fujii
    Tetrahedron, 55, 4999–5016 (1999)
17. Synthetic Studies on the Starfish Alkaloid Imbricatine. Construction of an ent-Imbricatine Framework
    M. Ohba, M. Imasho, and T. Fujii
    Chem. Pharm. Bull., 47, 83–89 (1999)
18. Chiral Synthesis of Tri-O-methylimbricatine, an Etherified Derivative of the Starfish Alkaloid Imbricatine
    M. Ohba, Y. Nishimura, M. Imasho, T. Fujii, J. Kubanek, and R. J. Andersen
    Terahedron Lett., 39, 5999–6002 (1998)
19. The Ipecac Alkaloids and Related Bases
    T. Fujii and M. Ohba
    The Alkaloids, 51, Chapter 3 (1998)
20. A Straightforward Preparation of Chiral 5-(Aminomethyl)oxazole Derivatives from a-Amino Esters and a-Lithiated Isocyanides
    M. Ohba, H. Kubo, S. Seto, T. Fujii, and H. Ishibashi
    Chem. Pharm. Bull., 46, 860–862 (1998)